COMPARE THE EFFECT OF 8 WEEKS OF AEROBIC INTERVAL TRAINING AND GLYCOGOL CONSUMPTION ON SERUM APELIN AND INSULIN RESISTANCE IN WOMEN WITH TYPE 2 DIABETES

Background: The purpose of this study was to investigate the effect of eight weeks of aerobic exercise and supplementation of gensing on homocysteine levels, tiroid hormon and insulin resistant in obese women with hypothyroidism. Methods: This study is quasi-experimental study. For this purpose, 40 obese women with hypothyroidism with an average age of 34.62 ± 3.55 years, weight 80.47 ± 3.85 kg and BMI of 32.2 ± 2.27 kg / m2, were randomly divided into four groups including aerobic training (10), ginsing (10), aerobic exercise and ginsing (10) and placebo (10) were divided.Aerobic exercise included 8 weeks of aerobic training, 3 sessions per week, 45 to 70 minutes, and 55 to 75% of maximum heart rate. Patients in the ginseng group and aerobic exercise with ginsing consumed each day a Jinsen's capsule containing 250 mg of granule Risomy ginseng powder was taken orally after 8 weeks for 8 weeks, while subjects in the placebo group received flour powdered capsules.Blood samples from the anterior vein were used to measure homocysteine, TSH, T3, T4, glucose and insulin before and after 8 weeks in four groups. For data analysis, dependent t-test and variance analysis were used (P≤0/05). Results: The results showed that the plasma homocysteine, TSH, glucose concentrate, insulin resistance and insulin resistance were significantly decreased in all three experimental groups while T3 and T4 increased (P <0.05). These indices in the control group were not changed (P <0.05). Conclusion: Therefore, aerobic exercise, along with supplementation with ginsing, can have an important role in preventing an increase in cardiovascular risk factors and hypothyroidism in obese women with hypothyroidism.